The true power of next-generation sequencing derives from the diversity of library creation methods available. There exist hundreds of NGS library creation methods tailored to different experimental approaches, with numerous commercial kits and variations for each method (for an introduction to library creation methods, see here: Illumina methods review). It is impossible for the UMGC to offer all of these various methods as “standard” services, with a fixed price and established expectations for turnaround and performance. However, we encourage researchers to contact us with requests for protocols they do not find here, as we are able to provide many of these as “custom” services (firstname.lastname@example.org). Here we list the subset of “standard” and “high-throughput” workflows that are offered as routine services in the UMGC.