Genomics Center

During the week of Monday, November 27 - Friday, December 1, we will be moving and consolidating two lab spaces into a new, centralized lab at 4Front Technology Campus in Oakdale, MN. The UMGC Snyder Hall lab on the St. Paul campus will be relocating to 4Front. Snyder Hall will remain a sample drop-off site for the St. Paul campus.

The Melov lab is developing workflows for profiling biopsies of human skeletal muscle and ovary to identify signatures of senescent cells, a classical hallmark of aging. Method development includes defining a transcriptional signature of senescence ("senotype") in cell culture models of senescence, and then identifying that signature in specific cells in biopsied tissue.

Join us for our 11th Annual GenoFest on Friday, October 6, 2023! This informative open house is for the UMN research community to learn about emerging trends in genomics technologies, future plans for the UMGC, and available resources and services. This year will include UMGC and technology presentations, lab tours, and a resource fair.

The UMGC welcomes the arrival of the AVITI sequencing instrument from Element Biosciences! With outstanding data quality and compatibility with Illumina libraries, the AVITI will be of particular interest to single-cell and spatial researchers and researchers who require ultra-high quality reads. The AVITI service will officially launch in August/September.

This symposium aims to bring together U of M investigators interested in single-cell methods to discuss key approaches in data analysis and interpretation and the latest developments in single-cell technologies. It will feature in-depth presentations from U of M experts in immunology and the biology of aging, as well as an open panel discussion. This event is co-organized by the U of M Genomics Center and the Minnesota Supercomputing Institute. 

MSI bioinformatics analysts have been working with U of M researchers to design and analyze experiments using the Nanostring GeoMx DSP. In this presentation, MSI will discuss important considerations and resources for experimental design. And also discuss details of GeoMx data analysis including a demonstration of how to use both the on-instrument software and R packages to analyze a complex melanoma data set from Dr. Alessio Giubellino.