PacBio and Phase Genomics Webinar

Part I: PacBio HiFi Sequencing & High-Resolution Metagenomics

Speaker: Amy Klegarth, Sequencing Applications Specialist, PacBio
Speaker: Greg Young, Senior Scientist, Field Applications, PacBio

HiFi reads from PacBio are transforming sequencing. With their unique combination of high accuracy and long read lengths, HiFi reads produce superior results across a range of applications, from creation of reference-quality de novo assemblies, to comprehensive variant detection and full-length transcript sequencing. PacBio has innovated workflows to enable the sequencing of high quality genomes from even the smallest organisms. Targeted and single-cell workflows further increase the breadth of questions that can be addressed using HiFi data.

In addition to overviewing key HiFi sequencing applications, we will take a deeper dive at utilizing HiFi for high resolution metagenomics. In this webinar, we discuss how HiFi sequencing identifies more unique taxa, increases and improves functional annotations, and results in higher quality metagenome assembled genomes (MAGs) relative to any other NGS technology.  HiFi sequencing only requires a few hundred nanograms of DNA per sample, and up to 8 metagenomic samples can be multiplexed per Sequel II 8M SMRT Cell. Please join us to learn more.

Part II: Ultra long range sequencing: deconvolution of complex genomes, metagenomes, karyotypes, and cancer

Speaker: Ben Auch, Scientist and Product Manager, Phase Genomics

Massively parallel sequencing is only uncovering a part of the story. Phase Genomics technology adds a new dimension of "ultra-long-range" information to next-generation sequencing platforms using proximity ligation (Hi-C) and integrated computational tools. Attend this webinar to learn how to separate metagenomes into genomes and connect mobile elements to their hosts, build chromosome-scale references from the toughest samples, and analyze structural variation and genome architecture – all with the same easy-to-use kit and analysis system. 

Part III: UMN Genomics Center

Speaker: Dr. Jon Badalamenti, UMGC PacBio Service Manager

Date: Tuesday, November 16, 2021
Time: 1:00 p.m. - 3:00 p.m.
View the recording

Do you have questions for the experts? Ben Auch and Ivan Liachko from Phase Genomics will be on-campus Thursday, November 18th, and Friday, November 19th for in-person or virtual project consultation. Sign-up here. Amy Klegarth from PacBio is also available for office hours. Sign-up here