Genomics Center

In order to see if sequencing results were comparable to those achieved by Illumina sequencers, the UMGC sequenced samples from multiple RNA-seq projects on the Illumina NovaSeq 6000 and the UG 100 for comparison. The main goal was to ask whether we can transition from the Illumina to the UG 100 sequencer and get equivalent results.

The UMN Spatialomics Initiative is a new coordinated effort that aims to accelerate spatialomic research by bringing together all relevant technical expertise in a single virtual location. The collection of resources on this new website will help researchers probe spatial interactions at the level of genomics and proteomics.

The increased adoption of the Element AVITI sequencers has allowed us to secure AVITI reagents at steeper discounts, enabling us to pass along further cost reductions in an end-of-year price drop—just in time for the holidays! Building on the ≈ 40% price reductions announced in July, AVITI sequencing costs have now decreased by an additional 20%, on average.

To assess comparability with Illumina sequencers, the UMGC performed 16S V4V5 amplicon sequencing on both the Illumina NextSeq 2000 and the Element AVITI. The primary objective was determining whether transitioning from the NextSeq platform to the AVITI would produce equivalent results.

A suite of AVITI sequencing systems is available at the UMGC, giving researchers expanded options for short-read, mid-throughput sequencing. The aim of this study was to evaluate quality metrics and gene expression counts for identical RNA-Seq samples sequenced using the AVITI and NovaSeq X Plus platforms.

The UMGC welcomes a new addition to its sequencing portfolio with the installation of the new AVITI24 system. Researchers will now have a new option for performing on flow cell multiomics on cells. The UMGC is the first site in the world to upgrade to the AVITI24.