The NovaSeq X Plus offers Illumina’s most advanced, powerful sequencing to date, surpassing the performance of the previous workhorse, the NovasSeq 6000, while dramatically lowering costs. It features a 2.5-fold increase in output, lower cost per gigabase and per read, streamlined informatics, and sustainability advancement.
The new XLEAP-SBS chemistry delivers increased speed and greater fidelity. Ultrahigh-density patterned flow cells contain tens of billions of nanowells at fixed locations, a design that provides even spacing of sequencing clusters. Flow cells are named according to the billions (B) of clusters each are capable of producing, and the UMGC offers the 10B and the 25B flow cells. Each flow cell contains 8 independent lanes, which can be used to load up to 8 separate library pools.
Highlighted applications
- Whole-genome sequencing*
- Whole-genome metagenomic or transcriptome sequencing
- Population-scale sequencing
*For most whole-genome projects, our per-sample whole-genome sequencing service will be the most cost-effective approach. This is an end-to-end service that includes sample quality control, library preparation, sequencing, primary data QC, and, for human and mouse projects, variant calling (VCFs) and summary reports.
More information
Outsourcing
The UMGC has determined that for the time being, access to the NovaSeq X Plus will be both faster and less expensive when outsourced, and we have partnered with reputable sequencing facilities to achieve this.
Output
The UMGC offers the 10B and the 25B flow cells only in the 300-cycle format (2 x 150 PE).
Benefits
- Add statistical power: Manage bigger sample cohort sizes for population-scale studies.
- Sequence more deeply: Identify rare genetic events for cancer and genetic disease applications.
- Examine multiple dimensions: Combine data from genomes, transcriptomes, and epigenomes for a more vivid picture of biological systems.
- Transition to high-resolution approaches: Including single-cell sequencing and spatial analysis for insights into complex tissues.
Questions
Please contact Aaron Becker or Elyse Cooper at [email protected] to receive a project proposal using the NovaSeq X Plus platform.
Contact us at [email protected] for a project quote on the Illumina instruments.
Fill out the sample submission form and email the completed form to [email protected].
Campus drop-off locations:
- 1-210 Cancer & Cardiovascular Research Building (Minneapolis campus)
- 20 Snyder Hall (St. Paul campus)
Shipping address:
UMN Genomics Center
ATTN: NGS Staff
3510 Hopkins Place N.
Building 4 Suite W402
Oakdale, MN 55128
612-625-7736
Please send the tracking information to [email protected].