The UMN Genomics Center offers advanced single-cell analysis with the 10x Genomics Chromium X, a next-generation microfluidic platform that delivers high-resolution cellular profiling. Using proprietary Gel Beads-in-Emulsion (GEM) technology, the system enables researchers to profile individual cells with exceptional precision, revealing rare cell types that can be missed with bulk RNA sequencing.
The UMGC can handle a range of single-cell projects, from pilot experiments to the highest-throughput studies, and offers the full portfolio of validated 10x single-cell assays, to give researchers flexibility for any experimental strategy.
Key Features of Our Service
- Complete, end-to-end workflow – from cell suspension loading and 10x library preparation to rigorous QC, sequencing, and data analysis. View our workflow for 10x projects.
- Library preparation options – train with the UMGC CoLab to run 10x assays yourself, or have our Single Cell Services team handle the processing for you.
- Flexible sequencing options – 10x libraries are run on our mid-throughput Element AVITI sequencers or production-scale Ultima UG100, enabling cost-effective sequencing and scalability for any project size.
- Expert guidance – support with experimental design and assay selection, including integration of Feature Barcoding and CellPlex, as well as supported Cell Hashing and CITE-seq protocols.
10x Single Cell Assays
The UMGC offers a wide and growing list of 10x single-cell assays to support a broad range of applications, including gene expression, chromatin accessibility, cell surface proteins, immune clonotype, antigen specificity, and CRISPR screens. We also support library preparation and sequencing of cDNA samples derived from 10x’s Visium spatial solution.
Start a Project
Whether a researcher is new to single-cell sequencing or one of our experienced users, we can help determine which 10x single-cell assay will best meet your experimental goals. The UMGC requests that researchers contact us at [email protected] for consultation on all incoming single-cell projects.
UMN Rates
10X Single Cell 3' and 5'
| Service | Savings Tier | Speed Tier | Priority Tier |
|---|---|---|---|
| Capture, reagents, cDNA & QC. Per sample. | $2,803.47 | $2,982.91 | $3,940.12 |
| Turnaround time. | 5 - 8 days | 3 - 6 days | 2 - 3 days |
| GEX library prep w/ QC. Sample 1. | $1,126.17 | $1,244.95 | $1,541.87 |
| GEX library prep w/ QC. Samples 2-8. | $270.43 | $319.20 | $406.11 |
| Turnaround time. | 9 - 16 days | 5 - 9 days | 3 - 4 days |
| VDJ library prep w/ QC. | $444.79 | $874.59 | $1,592.83 |
| Turnaround time. | 7 - 12 days | 5 - 8 days | 4 - 5 days |
| Add-on library w/ QC. | $258.24 | $442.40 | $747.39 |
| Turnaround time. | 4 - 6 days | 2 - 3 days | 1 - 2 days |
| cDNA and QC. | $101.75 | $170.68 | $354.34 |
| Turnaround time. | 5 - 8 days | 4 - 6 days | 2 - 3 days |
10X Single Cell Multiome
| Service | Savings Tier | Speed Tier | Priority Tier |
|---|---|---|---|
| Capture. Per sample. | $4,340.83 | $4,373.18 | $5,808.43 |
| Turnaround time. | 4 - 7 days | 2 - 5 days | 2 - 3 days |
| Multiome library prep w/ QC. Sample 1. | $1,406.73 | $1,811.24 | $2,630.57 |
| Multiome library prep w/ QC. Samples 2-8. | $550.99 | $885.49 | $1,494.81 |
| Turnaround time. | 13 - 22 days | 8 - 13 days | 4 - 6 days |
10X Single Cell Flex
| Service | Savings Tier | Speed Tier | Priority Tier |
|---|---|---|---|
| Flex hybridization. Up to 4 samples/pool.1 | $4,537.09 | $5,727.26 | $6,994.08 |
| Flex hybridization. Up to 16 samples/pool.2 | $8,189.76 | $10,951.83 | Inquire |
| Turnaround time. | 4 - 9 days | 4 - 6 days | 2 - 3 days |
| Flex library prep w/ QC. Pool 1. | $605.83 | $686.43 | $917.05 |
| Flex library prep w/ QC. Pool 2-4. | $215.14 | $259.39 | $332.73 |
| Turnaround time. | 5 - 13 days | 4 -7 days | 2 - 3 days |
Notes
1. Up to 20k cells per sample, 4 samples per pool, 80k cells per pool
2. Up to 20k cells per sample, 16 samples per pool, 320k cells per pool
Tiers: Turnaround time (TAT) is in business days. TAT is for the above-stated services and does not factor in the TAT for sequencing or other companion services. Availability for the Priority Tier is limited; contact [email protected] to see if this is a current option. More information about Pricing Tiers.
External Rates
10X Single Cell 3' and 5'
| Service | Savings Tier | Speed Tier | Priority Tier |
|---|---|---|---|
| Capture, reagents, cDNA & QC. Per sample. | $3,445.96 | $3,723.44 | $4,709.37 |
| Turnaround time. | 5 - 8 days | 3 - 6 days | 2 - 3 days |
| GEX library prep w/ QC. Sample 1. | $1,377.08 | $1,508.14 | $1,835.17 |
| GEX library prep w/ QC. Samples 2-8. | $325.23 | $378.47 | $472.07 |
| Turnaround time. | 9 - 16 days | 5 - 9 days | 3 - 4 days |
| VDJ library prep w/ QC. | $539.55 | $1,016.49 | $1,811.23 |
| Turnaround time. | 7 - 12 days | 5 - 8 days | 4 - 5 days |
| Add-on library w/ QC. | $310.25 | $513.97 | $849.98 |
| Turnaround time. | 4 - 6 days | 2 - 3 days | 1 - 2 days |
| cDNA and QC. | $188.43 | $298.79 | $500.97 |
| Turnaround time. | 5 - 8 days | 4 - 6 days | 2 - 3 days |
10X Single Cell Multiome
| Service | Savings Tier | Speed Tier | Priority Tier |
|---|---|---|---|
| Capture. Per sample. | $5,335.64 | $5,371.59 | $6,966.96 |
| Turnaround time. | 4 - 7 days | 2 - 5 days | 2 - 3 days |
| Multiome library prep w/ QC. Sample 1. | $1,714.76 | $2,162.41 | $3,066.92 |
| Multiome library prep w/ QC. Samples 2-8. | $677.31 | $1,049.06 | $1,726.22 |
| Turnaround time. | 15 - 25 days | 9 - 15 days | 5 - 7 days |
10X Single Cell Flex
| Service | Savings Tier | Speed Tier | Priority Tier |
|---|---|---|---|
| Flex hybridization. Up to 4 samples. | $5,129.48 | $6,898.12 | $7,528.47 |
| Flex hybridization. Up to 16 samples. | $9,244.62 | $13,140.05 | Inquire |
| Turnaround time. | 4 - 9 days | 4 - 6 days | 2 - 3 days |
| Flex library prep w/ QC. Pool 1. | $690.88 | $834.61 | $1,009.93 |
| Flex library prep w/ QC. Pool 2-4. | $249.87 | $313.64 | $375.29 |
| Turnaround time. | 5 - 13 days | 4 -7 days | 2 - 3 days |
Notes
1. Up to 20k cells per sample, 4 samples per pool, 80k cells per pool
2. Up to 20k cells per sample, 16 samples per pool, 320k cells per pool
Tiers: Turnaround time (TAT) is in business days. TAT is for the above-stated services and does not factor in the TAT for sequencing or other companion services. Availability for the Priority Tier is limited; contact [email protected] to see if this is a current option. More information about Pricing Tiers.
A planning meeting is needed to start a single-cell project to review your experimental goals and provide guidance on experimental design, as well as go over project logistics like turnaround estimates, scheduling, suspension buffer, and cell concentration requirements (varies based on assay).
Please note: Researchers need to schedule with the UMGC the delivery of a dissociated suspension of live cells or nuclei:
- We must have advance notice to have someone on standby to receive your cell suspension and prepare the reagents for cell capture.
- Your samples should be processed as quickly as possible.
- Email [email protected] a completed Sample Submission Form ahead of cell or nuclei suspension/s drop-off.
On the scheduled day of your capture, the UMGC staff requests to be kept apprised of your progress throughout your prep and notified if your delivery of cell or nuclei suspension/s on ice will be more than 30 minutes earlier or later than your appointment.
While we aim to be flexible and recognize that cell preparations can be labor and time-intensive, deliveries of cell suspensions more than 30 minutes outside of appointment times are subject to non-acceptance and cancellation of the capture.
Contact: [email protected]
Drop-off Location: 1-210 Cancer & Cardiovascular Research Building (CCRB, Minneapolis campus)