Genotyping Quality Control of DNA


Overview

High-throughput quality control for genotyping involves functional assays called “QC1”, “QC2”, and “QC3”. Unlike simple DNA quantification, which may fail to detect DNA impurities, these functional assays predict performance of DNA in genotyping. These assays are also useful for quantifying DNA that may be chemically pure, but of mixed origin (e.g., human buccal DNA that contains microbial DNA contamination). Another use for these assays is ensuring that fragmented DNA is of adequate length for PCR amplification.

Contact genotype@umn.edu.

Pricing

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UMN Rates

ServiceSavings TierSpeed TierPriority Tier
QC1. Per 96-well Plate.$57.73$106.45$131.40
Turnaround time.5 to 10 days3 to 4 days1 to 2 days
QC2. Per 96-well Plate.$64.12$113.09$139.50
Turnaround time.5 to 10 days3 to 4 days1 to 2 days
QC1 and QC2. Per 96-well Plate.$121.85$219.54$270.90
Turnaround time.10 to 20 days6 to 8 days2 to 4 days


Notes
QC1: A non-allelic Q-PCR assay that measures the quantity of PCR-amplifiable human DNA. QC2: An end-point Taqman SNP genotyping assay that is a sensitive indicator of sample-to-sample cross-contamination.  
Tiers: Turnaround time (TAT) is in business days. Availability for the Priority Tier is limited; contact genotype@umn.edu to see if this is a current option.

External Rates

ServiceSavings TierSpeed TierPriority Tier
QC1. Per 96-well Plate.$73.64$127.76$155.58
Turnaround time.5 to 10 days3 to 4 days1 to 2 days
QC2. Per 96-well Plate.$81.79$136.27$165.62
Turnaround time.5 to 10 days3 to 4 days1 to 2 days
QC1 and QC2. Per 96-well Plate.$155.43$264.03$321.20
Turnaround time.10 to 20 days6 to 8 days2 to 4 days


Notes
QC1: A non-allelic Q-PCR assay that measures the quantity of PCR-amplifiable human DNA. QC2: An end-point Taqman SNP genotyping assay that is a sensitive indicator of sample-to-sample cross-contamination.  
Tiers: Turnaround time (TAT) is in business days. Availability for the Priority Tier is limited; contact genotype@umn.edu to see if this is a current option.

Guidelines

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Submission

How to Order


Complete the DNA Submission form and email the completed form to genotype@umn.edu with your samples.

Researchers should submit 10 ng of DNA per each QC assay in a 96-well plate according to the Submission Guidelines below.

DNA Submission Guidelines.

Deliverables

An Excel report is emailed to client.

FAQ

What is the turnaround time?


The UMGC guarantees a turnaround time of 3 days.