Join the Spatialomics Interest Group

The Spatialomics Interest Group (SIG) is a forum to connect UMN researchers from different disciplines with experts in spatial biology and with UMN core facilities, who will coordinate the efforts and workflows for this multi-disciplinary field. The purpose of the group is to provide structured roundtable discussions and collaboration among interested parties that will enable the implementation and adoption of spatial technologies for the UMN research community.

Technologies: NanoString GeoMx DSP, 10X Genomics Visium, IONPath MIBI, and more
Cores: UMN Genomics Center and the University Imaging Center
 
Meetings will be ~monthly and each meeting will highlight a particular spatial technology. 

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Main Activities

  • Members will share their experiences and results with nascent spatial technologies.
  • Cores and vendors will assist early adopters in evaluating technologies and will assist with their initial experimental plan (number of samples, technique sharing, QC checkpoints, sequencing depth, etc).
  • The entire group will provide guidance and information on how researchers can apply a spatial technology to achieve a specific research goal.
  • Vendors will present technical details about how to get started with their technologies (experimental set-up, sample requirements, reagents, analysis, troubleshooting, etc.)
  • The entire group with discuss proposals for funding equipment and resources for spatial biology at the UMN.  (e.g., AIAC grant opportunities).
  • Outcome: Dialogue and cooperation among the core labs providing tissue and microscopic services, next-generation sequencing, and analysis.

2022-2023 Meetings

Tuesday, September 27, 2022   |  1:00 - 2:00 p.m. 
Title: Analysis of chemotherapy response in ovarian cancer patients using the GeoMX digital spatial profiler
Presenter: Tim Starr, Ph.D. - Associate Professor, Department of Obstetrics, Gynecology and Women's Health 
Hybrid Format: 1-101 Microbiology Research Facility (MRF) and Zoom

Tuesday, October 18, 2022   |  11:00 a.m. - 12:00 p.m. 
Title: Spatial transcriptomics of human liver to characterize senescence with aging and fibrosis
Presenter: Elizabeth Thompson, Ph.D. - Research Support Manager (Niedernhofer Lab, Institute on the Biology of Aging & Metabolism)
Format: Zoom

Tuesday, November 29, 2022   |  11:30 a.m. - 12:30 p.m. 
Title: RHAMM-associated immune infiltration in breast cancer tumor microenvironment revealed by GeoMx DSP & MIBI
Presenter: Yuyu He - Researcher (Nelson lab, Lab Med and Pathology) 
Format: Zoom

Tuesday, January 24, 2023   |  10:00 a.m. - 11:00 a.m. 
Topic: Researcher experience using the Nanostring CosMx Spatial Molecular Imager to study spatially resolve transcripts of interest
Presenter: Miranda E. Orr, PhD - Wake Forest University School of Medicine Assistant Professor, Gerontology and Geriatric Medicine
Format: Zoom

2021-2022 Meetings

Wednesday, September 22, 2021  |  10 - 11:15 a.m. 
Discovering New Insights Using NanoString DSP and Whole Transcriptome Analysis
Recording

Wednesday, October 13, 2021   |  10 - 11:00 a.m. 
Dr. Christine Henzler from MSI presenting on data analysis services
Recording

Wednesday, October 27, 2021   |  10 - 11:15 a.m. 
10X Genomics: Breaking spatial barriers with Visium Spatial solutions
Recording

Wednesday, November 17, 2021   |  10 - 11:00 a.m. 
The CODEX Solution: Comprehensive Solution for Spatially Resolved, Multiplexed Imaging
Recording

Wednesday, December 8, 2021   | 10 - 11:00 a.m. 
Presentations by Dr. Casey Dorr (GeoMX WTA) and Dr. Yuyu He (MIBI)
No recording due to unpublished, preliminary data.

Wednesday, February 16, 2022  |  11:00 a.m. - 12:00 p.m. 
NanoString CosMx Spatial Molecular Imager
Recording

Wednesday, March 16, 2022  |  11:00 a.m. - 12:00 p.m. 
Defining high-plex spatialomics: from GeoMx data to discovery
Recording

Wednesday, April 13, 2022  |  11:00 a.m. - 12:00 p.m. 
10X Genomics: Breaking spatial barriers with Visium Spatial solutions
Recording

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Questions?


Contact the UMGC at umgc@umn.edu