Epigenomics

Note: The UMGC will be closed from Monday, May 16 - Friday, May 20, and we will not be receiving or processing samples during this week.


There are a wide variety of methods for studying epigenetic phenomena in a high-throughput fashion, and among the most widely used is the measurement of DNA methylation profile, achieved via array- or sequencing-based platforms on bisulfite-treated DNA. Bisulfite treatment – which in combination with molecular tricks converts C to T in DNA while leaving methyl-C residues unchanged – permits a DNA methylation profile to be scored by genotyping or sequencing assays.

In this section, we list services for array-based DNA methylation analysis, including bisulfite treatment and the Illumina Infinium MethylationEPIC platform.

For Next-generation Sequencing-based DNA methylation services, see the NGS Library DNA Methylation section.