Next-Generation Sequencing

The UMGC provides the latest and most powerful next-generation sequencing platforms from Illumina and Element Biosciences, giving researchers a wide range of cutting-edge sequencing solutions to fit any project scale, budget, and turnaround. Our highly trained NGS scientists have direct experience and knowledge of operating complex technical instrumentation while balancing the high-throughput needs of our research community.

As a Certified Service Provider for Illumina, we undergo rigorous annual certification to guarantee our clients receive the highest quality data using the most up-to-date workflows. In addition, the strict process regulation and quality control checks required for diagnostic testing in our CLIA-certified lab are optionally applied to all our research samples. See a summary of our high-output sequencing options.

Advantages of our NGS service

  • Highly experienced NGS team providing unparalleled skill and sequence quality for an academic core facility.
  • Flexible sequencing options from a diverse array of instruments ranging from small to production-scale capacities.
  • Competitive pricing at just $2.81/Gb for UMN researchers on the production-scale Illumina NovaSeq X Plus instrument.
  • Expert NGS consultation to guide researchers on using the best NGS platform for their research goals.

Successful Illumina sequencing is not only dependent on the quality of the DNA or RNA submitted, but also on the quality of the library created and in the selection of the appropriate library kit. Our highly experienced NGS team consistently produces uniform library fragment sizes for optimal cluster generation and maximal data output of your flow cell lane. Alternatively, researchers can submit their own libraries for full QC workup and use our sequencing-only service.

We offer a broad range of sequencing instrumentation with different output capacities and read lengths to partner with our comprehensive selection of library creation services.


Whether a client is new to NGS or one of our regular users, we can help determine which instrument and application best meet a project’s goal. Clients are encouraged to contact our NGS team for consultation on experimental design, library creation methods, or sequencing options at