AVITI Upgrade Complete: Sequencing Costs Drop Again at UMGC

September 15, 2025

The UMN Genomics Center is pleased to announce the successful upgrade of our five Element AVITI24 sequencers to the latest operating system. This upgrade delivers a 50% increase in output for 150-cycle and 300-cycle kits (600-cycle kit output unchanged), while AVITI pricing remains the same.

300-cycle Kit	Previous Output	Upgraded Output
Low Output Run	250 M	375 M
Medium Output Run	500 M	750 M
High Output Run	1 B	1.5 B

As a result, AVITI sequencing is now 33% less expensive per million reads (or per GB) compared to fiscal year 2025 (FY25). This marks the third drop in AVITI sequencing cost over the past two years, dropping by a staggering 62% – 71% since FY24, thanks to ongoing innovation by Element and the UMGC’s commitment to the platform at scale.

Bar chart showing AVITI pricing evolution at UMGC for FY24-26 across 150-cycle, 300-cycle, and 600-cycle kits. — See full data for the Evolution of UMN AVITI Pricing.

The AVITI now saves researchers several hundred to one thousand dollars per billion reads, relative to the most affordable Illumina platform. Best of all, these gains come with no compromise in quality. Sequencing on the AVITI continues to deliver Q-scores > 40, as confirmed in published studies and our own field testing of the new operating system. Researchers finally have the rare trifecta with the AVITI—fast, affordable, and high-quality sequencing.

Learn more about the future of sequencing at GenoFest, the UMGC’s annual open house, on Friday, October 3. For details on AVITI sequencing or to discuss your next project, contact us at [email protected].